A US move to put Huawei on a trade blacklist "sets a dangerous precedent" that will harm billions of consumers, the firm's top legal officer said.
Speaking at a press conference, Song Liuping said the trade ban would also "directly harm" American companies and affect jobs.
Washington recently added Huawei to a list of companies that US firms cannot trade with unless they have a licence.
The trade ban is part of a wider battle between the US and Huawei.
Washington has moved to block the Chinese company, the world's largest maker of telecoms equipment, on national security concerns.
Huawei has repeatedly denied claims the use of its products presents security risks, and says it is independent from the Chinese government.
"Politicians in the US are using the strength of an entire nation to come after a private company," Mr Song said.
He said the decision to put Huawei, which is also the world's second largest smartphone maker, on the so-called "entity list" would have far-reaching implications.
"This decision threatens to harm our customers in over 170 countries, including more than three billion consumers who use Huawei products and services around the world."
"By preventing American companies from doing business with Huawei, the government will directly harm more than 1,200 US companies. This will affect tens of thousands of American jobs."